In the Limelight: January 2020

Centrosomes back in the limelight.

Centrosomes and centrioles were ‘born’ towards the end of the nineteenth century when they were first spotted and studied by astute cell and developmental biologists, including Edouard Van Beneden, as well as Theodor Boveri and Walther Fleming, who coined the terms ‘centrosome’ and ‘centriole’, respectively, that still designate these structures today. There was much initial excitement about ce...

Coronaviruses in the limelight.

Lysophospholipids in the limelight

Lysophosphatidic acid (LPA) is a serum phospholipid that evokes growth factor-like responses in many cell types through the activation of its G protein-coupled receptors. Although much is known about LPA signaling, it has remained unclear where and how bioactive LPA is produced. Umezu-Goto et al. (2002)(this issue, page 227) have purified a serum lysophospholipase D that generates LPA from lyso...

Spatial analysis of the COVID-19 prevalence pattern in Yazd province, Central part of Iran (February 2020 to January 2021)

Abstract Introduction:  . Yazd province is the center of Iran and the highway for travelers to other cities. This province is susceptible to disease transmission in Iran.   this study aimed to spatial analysis of corona virus prevalence,  predicting the spread and determination of hot spot  areas in Yazd province, central part of Iran. Methods:  This analytical Cross-sectional study was condu...

Dendritic Cells Bask in the Limelight

Ralph Steinman is to receive the 2007 Albert Lasker Award for Basic Medical Research for his discovery of dendritic cells and his path-breaking work demonstrating their central role as the principal antigen-presenting cells of the immune system and key activators of T cell responses.